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Saturday, October 26, 2013

Increasing insulin levels can aid muscle building in the elderly


When most people think of insulin, they think of diabetes - a disease that arises when, for one reason or another, insulin can not do the critical job of helping the body process sugar. But the hormone has another, more well-known function. Also needed for muscle growth, increasing blood flow through muscle tissue, encouraging nutrients to disperse from blood vessels and its serving as a biochemical signal to boost muscle protein synthesis and cell proliferation.

 Recently, scientists have recognized that the loss of responsiveness to insulin plays a major role in the loss of physical strength that occurs as people grow older. Now, University of Texas Medical Branch at Galveston researchers have shown that by increasing insulin levels above the normal range in elderly test subjects, they can restore the impaired muscle-building process responsible for age-related physical weakness. "Insulin is normally secreted during food intake," said Dr.. Elena Volpi, senior author of a paper on the study to be published in the September issue of Diabetologia.

"When you give insulin intravenously and increase the blood levels of insulin in the same amount produced after a meal, you will see that young people it stimulates protein synthesis and muscle growth, while older people are not really. Yet when we gave seniors double the insulin they normally produce after eating, their muscles were stimulated as young people. " Volpi and his co-authors - postdoctoral fellows Satoshi Fujita and Kyle Timmerman, graduate student Erin Glynn and Professor Blake B. Rasmussen - worked with 14 elderly volunteers to assess the response of thigh muscle to the two different blood insulin levels, established by infusion into the main artery of the thigh.

Blood samples taken from catheters inserted in the femoral artery and vein of each subject enabled the researchers to calculate blood flow and muscle protein synthesis, and muscle biopsies allowed them to measure the level of signaling of molecules involved in the growth of muscle protein. All the data pointed in the same direction, showing that a blood insulin level double that produced by a typical meal seems to turn back the clock on elderly thigh muscle.

For more about body building:

http://www.healthcureview.com/somanabolicmusclemaximizer-review/

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